MicroVue™ PYD EIA
The MicroVue PYD provides a quantitative measure of pyridinium cross-links (Pyd and Dpd) as an indicator of type I collagen resorption, especially bone collagen.
Product Specifications
| Citations | 7 | 
|---|---|
| Specimen | 
                      Urine 50 μL  | 
               
| LLOQ | 15 nmol/L | 
| ULOQ | 750 nmol/L | 
| Assay Time | 4 hours | 
| Cross Reactivity | 
                      Cynomolgous monkey, Dog, Guinea Pig, Horse, Mouse, Pig, Rabbit, Rat, Rhesus monkey, Sheep  | 
               
Ordering Information
| Catalog Number | 8010 | 
|---|---|
| Catalog Number (CE) | |
| Size | 96 wells/test | 
| Price (USD) | $995.00 | 
| Price (EURO) | 700,00 € | 
Contact us
| US Phone | +1 (858) 552 1100 | 
|---|---|
| EU Phone | +353 (91) 412 474 | 
| US Email | contact-us@quidelortho.com | 
| EU Email | contact-emea@quidelortho.com | 
- Specifications
 - Citations
 - Certificate of Analysis
 
Specifications
| Description | 
                      The MicroVue PYD provides a quantitative measure of pyridinium cross-links (Pyd and Dpd) as an indicator of type I collagen resorption, especially bone collagen.  | 
               
|---|---|
| Size | 96 wells/test | 
| Form | 
                      96 well plate with 12 eight-well strips in a resealable foil pouch  | 
               
| Specimen | Urine 50 μL | 
| Limit of Detection (LOD) | 7.5 nmol/L | 
| Lower Limit of Quantitation (LLOQ) | 15 nmol/L | 
| Upper Limit of Quantitation (ULOQ) | 750 nmol/L | 
| Intra Assay | 6.6–9.9% | 
| Inter Assay | 3.9–11.2% | 
| Standards | 6 | 
| Controls | 2 | 
| Sample Values | 
                      Females (Ages >25) (premenopausal) 16.0–37.0 nmol PYD/mmol Creatinine, Males 12.8–25.6 nmol PYD/mmol Creatinine  | 
               
| Assay Time | 4 hours | 
| Cross Reactivity | 
                      Cynomolgous monkey, Dog, Guinea Pig, Horse, Mouse, Pig, Rabbit, Rat, Rhesus monkey, Sheep  | 
               
| Storage | 
                      Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components  | 
               
| Background | 
                  
                      MicroVue PYD provides a quantitative measure of pyridinium cross-links (Pyd and Dpd) as an indicator of type I collagen resorption, especially bone collagen. Pyd and Dpd are excreted unmetabolized in urine. MicroVue PYD is intended for use as an indicator of type I collagen resorption, especially bone collagen.  | 
               
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details | 
|---|---|---|---|---|---|
| 2012 | ELISA  | 
               Human | 
                   Urine  | 
               
                   Hematopoietic cell transplantation  | 
            |
| 
                   Biomarkers of bone remodeling in children with mucopolysaccharidosis types I, II, and VI.  | 
               2014 | ELISA  | 
               Human | 
                   Urine  | 
               
                   Mucopolysaccharidosis Types I, II, and VI, children  | 
            
| 2018 | ELISA  | 
               Human | 
                   Lung Tissue  | 
               ||
| 2009 | ELISA  | 
               Mouse | 
                   Urine  | 
               ||
| 2011 | ELISA  | 
               Mouse | 
                   Artery Tissue  | 
               ||
| 2016 | ELISA  | 
               Mouse | 
                   Urine  | 
               ||
| 2016 | ELISA  | 
               Rat | 
                   Heart Tissue  |